SETD8 Peptide
Ref. 3D-CRB1001168
1mg | 271.00 € | ||
500µg | 198.00 € |
Product Information
- H-KRHR(nL)VLR-OH
Setd8 is a member of the SET domain containing family of proteins and is the sole methyltransferase that catalyses monomethylation of lysine 20 on histone H4 (H4K20me1). This histone modification is involved in regulating DNA replication, chromosome condensation and gene expression.Setd8 is widely expressed and in addition to modifying histone H4, it can modify non-histone proteins, including p53. Setd8 has been shown to play a role in maintaining skin differentiation and is dysregulated in multiple cancer types.
Chemical properties
Technical inquiry about: 3D-CRB1001168 SETD8 Peptide
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