Cyclo(-RGDyK)
Ref. 3D-CRB1001169
1mg | 452.00 € | ||
500µg | 371.00 € |
Product Information
- [LacN(0,5)]RGD(dY)K
The cyclic pentapeptide cyclo(-Arg-Gly-Asp-d-Phe-Lys-) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(-Arg-Gly-Asp-d-Phe-Val), is a promising anti-cancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells.Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell and cell-matrix interactions. In a suitably labelled form, these peptides may serve as useful tools for diagnostic imaging and peptide targeted therapy of some types of cancer.
Chemical properties
Technical inquiry about: 3D-CRB1001169 Cyclo(-RGDyK)
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