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RAGE antagonist peptide

Ref. 3D-CRB1001194

1mg
254.00€
500µg
186.00€
RAGE antagonist peptide
Biosynth

Product Information

Name:RAGE antagonist peptide
Synonyms:
  • Ac-ELKVLMEKEL-NH2
Brand:Biosynth
Description:RAGE antagonist peptide is an S100P-derived peptide based competitive antagonist for receptor for advanced glycation end product (RAGE). Recent studies have shown it to disrupt the interaction between RAGE and its ligands, such as S100P, S100A4 and HMGB-1 in binding assays and in multiple cancer cell lines. As well as this, it also blocks RAGE-dependent NF-kB activation in MPanc96, MOH and HPAF II tumor cell lines.Systemic administration of RAGE antagonist peptide also diminishes NF-kB signaling in vivo and significantly reduces glioma tumour growth in murine models.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:1,271.7 g/mol

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