Urumin
Ref. 3D-CRB1001196
| 1mg | 271.00 € | ||
| 500µg | 198.00 € |
Product Information
- H-IPLRGAFINGRWDSQCHRFSNGAIACA-OHIPLRGAFINGRWDSQCHRFSNGAIACA-acidH-Ile-Pro-Leu-Arg-Gly-Ala-Phe-Ile-Asn-Gly-Arg-Trp-Asp-Ser-Gln-Cys- His-Arg-Phe-Ser-Asn-Gly-Ala-Ile-A la-Cys-Ala-OH
Urumin is a veridical host defence peptide against influenza A virus.The peptide specifically targets the evolutionarily conserved H1 hemagglutinin stalk region of H1-containing influenza A viruses.Urumin has been used against drug-resistant influenza A viruses that are resistant against oseltamivir, zanamivir and peramivir. While its mechanism of action is not fully understood, urumin seems to inhibit viral growth by physically destroying influenza A virions, and is able to protect naive mice from doses of influenza A infection as high as 2 times the LD50. Because of its specific targeting of the hemagglutinin stalk region of the influenza A virus, the mechanism of action of urumin is similar to that of antibodies induced in the body by universal influenza vaccines.
Chemical properties
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