BMF
Ref. 3D-CRB1001274
1mg | 271.00 € | ||
500µg | 198.00 € |
Product Information
- Ac-HQAEVQIARKLQLIADQFHR-NH2Ac-HQAEVQIARKLQLIADQFHR-amideAc-His-Gln-Ala-Glu-Val-Gln-Ile-Ala-Arg-Lys-Leu-Gln-Leu-Ile-Ala-Asp-Gln-Phe -His-Arg-NH2
Bcl-2-modifying factor (Bmf) belongs to the BH3-only class of Bcl-2 family proteins (along with Bim). Bmf has pro-apoptotic activity and can trigger mitochondrial apoptosis via inhibition of CAP-dependent protein synthesis, it is also involved in B cell development and anoikis. Bmf activity is regulated by dynein light chain (DYNLL) 1 and 2, via inducing its homo-dimerization and leading to the formation of ternary complexes (such as Bim-DYNLL-Bmf).
Chemical properties
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