AYPGFK Protease-Activated Receptor-4 (PAR-4)
Ref. 3D-CRB1001374
| 1mg | 271.00 € | ||
| 500µg | 198.00 € |
Product Information
- H-AYPGKF-NH2
Protease activated receptors (PARs) are a distinctive four-member family of seven transmembrane G protein-coupled receptors (GPCRs) widely expressed in inflammatory cells. PARs are cleaved by certain serine proteases to expose a tethered ligand domain, this ligand domain then binds to and activates the receptors to initiate multiple signalling cascades. These PAR-activating proteases therefore represent PAR agonists. This PAR-4 agonist peptide represents the N-terminal sequence of the 'tethered ligand' and is therefore capable of activating the receptor independently of N-terminal proteolysis.
Chemical properties
Technical inquiry about: 3D-CRB1001374 AYPGFK Protease-Activated Receptor-4 (PAR-4)
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