hsBCL9CT-24
Ref. 3D-CRB1001394
1mg | 574.00 € | ||
500µg | 452.00 € |
Product Information
- [Stp(6,10)]Ac-LQTLR(S5)IQR(S5)L(2Nal)-NH2
- 2Nal is 2-naphthyl-alalnine Ac-LQTLR-[X]-IQR-[X]-L-[2-Nal]-amide stapledAc-Leu-Gln-
Blocks the Wnt pathway and inhibits the expression of TGFb1 in CT26 colon carcinoma cells, leading to the reduction of CCL20 and CCL22, two TGF-b- dependent chemokines critical for Treg cell recruitment into the tumour microenvironment. hsBCL9CT-24 shows robust antitumour efficacy across multiple in vivo models.
Chemical properties
Technical inquiry about: 3D-CRB1001394 hsBCL9CT-24
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