Triptorelin acetate
Ref. 3D-CRB1001490
| 1mg | 271.00 € | ||
| 500µg | 198.00 € |
Product Information
- pE-HWSY(dW)LRPG-NH2 acetate salt[Pyr]-HWSY-[D-Trp]-LRPG-amide acetate salt[Pyr]-His-Trp-Ser-Tyr-[D-Trp]-Leu-Arg-Pro-Gly-NH2 acetat e salt
Triptorelin is an agonist of gonadotrophin-releasing hormone (GnRH-R). Androgen-deprivation therapy (ADT), based on GnRH agonists and antagonists, is the standard therapeutic approach for prostate cancer (PCa) patients. In castration-resistant prostate cancer (CRPC) GnRH agonists are associated with significant anti-proliferative/pro-apoptotic, anti-metastatic and anti-angiogenic effects, mediated by the Gαi/cAMP signalling cascade. The tryptophan residue in this peptide is replaced with the D-amino acids making the peptide resistant to degradation from proteases and therefore increasing the half-life of the peptide in vivo. Peptide is for research purposes only, strictly not for human use.
Chemical properties
Technical inquiry about: 3D-CRB1001490 Triptorelin acetate
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