CoV Main Protease (Mpro) Substrate
Ref. 3D-CRB1001501
1mg
254.00€
500µg
186.00€
Product Information
Name:CoV Main Protease (Mpro) Substrate
Synonyms:
- H-AVLQSGFR-OHAVLQSGFR octapeptide
Brand:Biosynth
Description:Substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro). The substrate sequence is derived from residues P4-P5' of the SARS-CoV Mpro N-terminal autoprocessing site and was identified by a docking study. This substrate binds to and acts as a competitive inhibitor of SARS-CoV Mpro, (3CLpro).Experiments show that the octapeptide AVLQSGFR is bound to SARS-CoV Mpro through six hydrogen bonds. It is an effective inhibitor of SARS coronavirus with an EC50 of 2.7 x 10-2 mg/L and is able to block replication of the virus. The octapeptide also shows no detectable toxicity in the host cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
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