M12 muscle-homing peptide
Ref. 3D-CRB1001635
| 1mg | 271.00 € | ||
| 500µg | 198.00 € |
Product Information
- H-RRQPPRSISSHP-OH
Gene therapy is potentially an ideal treatment for muscle tissue myopathies but targeting remains an issue. The large volume of muscle in the body versus the requirement for tissue-specificity is of particular concern. This heptapeptide has been shown to preferentially bind myofibers and thus can be used to study targeting of peptide/gene- delivery to muscle tissue. Research into gene therapy of Duchenne muscular dystrophy (DMD) and Spinal muscular atrophy (SMA) has been of particular interest with muscle targeting peptides.- This product has been shown to orientate to muscle and heart tissue and when conjugated to a phosphorodiamidate morpholino oligomer (PMO)-increases dystrophin expression by 25%. This product already shows ideal placement to continue cardiac research to overcome some of these issues.
Chemical properties
Technical inquiry about: 3D-CRB1001635 M12 muscle-homing peptide
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