Biotin-Influenza A NP (147-155) (H-2Kd)
Ref. 3D-CRB1001751
| 1mg | 354.00 € | ||
| 500µg | 271.00 € |
Product Information
- Biot-TYQRTRALV-OH
Influenza A nucleoprotein (NP) residues 147-155 (TYQRTRALV) is from a conserved region of the nucleoprotein that is positively selected. NP (147-155) is an effective immunodominant CTL epitope MHC allele H-2Kd in mice that can induce an effective antigen-specific immunity. This was validated by HLA binding and cytotoxicity assays in human cells. Immunisation of mice with the NP (147-155) offers protection against a fatal dosage of influenza. In addition, the NP (147-155) epitope can stimulate antigen-specific T cells in T cell assays such as ELISPOT to understand humoral responses to viral infection. Further work with the NP (147-155) epitope can help new flu vaccine design to provide more effective protection. This epitope is provided with a C-terminal biotin sequence for easier purification and detection.
Chemical properties
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