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SARS-CoV-2 NSP13 (476-490)
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SARS-CoV-2 NSP13 (476-490)

Ref. 3D-CRB1001801

1mg
271.00 €
500µg
198.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
SARS-CoV-2 NSP13 (476-490)
Synonyms:
  • H-YKGVITHDVSSAINR-OH
Description:

The SARS-CoV-2 non-structural protein 13 (NSP13) has been identified as a target for anti-viral therapeutics due to its highly conserved sequence and is essential for viral replication. NSP13 is part of the helicase superfamily 1B. As an NTPase and RNA helicase, NSP13 binds to RNA-dependent RNA polymerase and acts in concert with the replication-transcription complex to stimulate backtracking and further activate NSP13 helicase activity. These factors make NSP13 a good target for developing new antiviral drugs. In addition, the identification of epitopes within the NSP13 sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. NSP13 (476-490) is an epitope candidate with various predicted HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,658.9 g/mol
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Hazard Info

UN Number:
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Forbidden to fly:
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