![[5-FAM]-CRAMP (6-39)](https://static.cymitquimica.com/products/3D/img/CRB1100256.png "Click to enlarge")
[5-FAM]-CRAMP (6-39)
Ref. 3D-CRB1100256
| 1mg | 626.00 € | ||
| 100µg | 371.00 € | ||
| 500µg | 452.00 € |
Product Information
- 5fam-GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ-OH[5-FAM]-GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ-acid[5-FAM]-Gly-Leu-Leu-Arg-Lys-Gly-Gly-Glu-L ys-Ile-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln- Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-Val-Pro-Gln-Pro-Glu-Gln-OH
Amino acids 6-39 of the cathelicidin-related anti-microbial peptide (CRAMP), the mouse homologue of the human LL-37 anti-microbial peptide.CRAMP possesses potent anti-bacterial activity against Gram-positive and Gram-negative bacterial strains with no haemolytic activity. As well as displaying direct anti-microbial activity, CRAMP also binds to lipopolysaccharide (LPS) to neutralise its activity.CRAMP is a cationic peptide, encoded for by the Camp gene and is highly expressed in bone marrow. Its expression is up-regulated by infectious and inflammatory signals and it is secreted by cells such as neutrophils epithelial cells and macrophages.This peptide contains N-terminal 5-Carboxyfluorescein (5-FAM), a widely used, green fluorescent tag
Chemical properties
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