[5-FAM]-CRAMP (6-39)

Ref. 3D-CRB1100256

Product Information

• Name: [5-FAM]-CRAMP (6-39)
• Synonyms: 5fam-GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ-OH[5-FAM]-GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ-acid[5-FAM]-Gly-Leu-Leu-Arg-Lys-Gly-Gly-Glu-L ys-Ile-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln- Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-Val-Pro-Gln-Pro-Glu-Gln-OH
• Brand: Biosynth
• Description: Amino acids 6-39 of the cathelicidin-related anti-microbial peptide (CRAMP), the mouse homologue of the human LL-37 anti-microbial peptide.CRAMP possesses potent anti-bacterial activity against Gram-positive and Gram-negative bacterial strains with no haemolytic activity. As well as displaying direct anti-microbial activity, CRAMP also binds to lipopolysaccharide (LPS) to neutralise its activity.CRAMP is a cationic peptide, encoded for by the Camp gene and is highly expressed in bone marrow. Its expression is up-regulated by infectious and inflammatory signals and it is secreted by cells such as neutrophils epithelial cells and macrophages.This peptide contains N-terminal 5-Carboxyfluorescein (5-FAM), a widely used, green fluorescent tag

Chemical properties

• Molecular weight: 4,236.91 g/mol