[5-FAM]-PR9

Ref. 3D-CRB1100285

Product Information

• Name: [5-FAM]-PR9
• Synonyms: 5fam- FFLIPKGRRRRRRRRR-NH2[5-FAM]- FFLIPKGRRRRRRRRR-amide[5-FAM]-Phe-Phe-Leu-Ile-Pro-Lys-Gly-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-N H2
• Brand: Biosynth
• Description: CPPs can transport molecules such as nucleic acids, proteins and imaging agents into cells of inter-est. PR9, Pas non-arginine, is an arginine rich CPP. It is composed of the nona-arginine: R9 and Pas which is a peptide penetrating accelerating sequence and it functions to export molecules out of endocytic vesicles. During a study in which PR9 was in complex with a Quantum dot probe (QD) it was evident that the PR9/QD complex was transported into the cell through endocytosis where it co-localises with actins, lysosomes, early endosomes and the nucleus. Due to the non-toxicity of the PR9/QD complex it can be used as a safe vector for biomedical purposes.It contains 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag.

Chemical properties

• Molecular weight: 2,584.01 g/mol