[5-FAM]-MAP

Ref. 3D-CRB1100286

Product Information

• Name: [5-FAM]-MAP
• Synonyms: 5fam-KLALKLALKALKAALKLA-NH2[5-FAM]-KLALKLALKALKAALKLA-amide[5-FAM]-Lys-Leu-Ala-Leu-Lys-Leu-Ala-Leu-Lys-Ala-Leu-Lys-Ala-Ala-Leu-Lys -Leu-Ala-NH2
• Brand: Biosynth
• Description: Amphipathic alpha-helical cationic antimicrobial peptides (AMPs) are rapidly bactericidal and have broad spectrum activity. As AMPs have non-specific modes of action involving membrane disruption, bacteria are less likely to develop resistance to them (unlike traditional antibiotics). KLAL is a model compound to form amphipathic helices that are able to bind to membranes and increase the membrane permeability. KLAL model peptides may also form a β-structure under appropriate conditions. Peptide is labelled with an N-terminal 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.

Chemical properties

• Molecular weight: 2,234.76 g/mol