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SMAC/DIABLO [Lys(5-FAM)]
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SMAC/DIABLO [Lys(5-FAM)]

Ref. 3D-CRB1100325

1mg
371.00 €
500µg
271.00 €
Estimated delivery in United States, on Friday 13 Dec 2024

Product Information

Name:
SMAC/DIABLO [Lys(5-FAM)]
Synonyms:
  • AVPIAQKSE--acidH-Ala-Val-Pro-Ile-Ala-Gln-Lys-Ser-Glu--OH(N-Cbz-Nle-KRR)2-[R110]
  • (N-Cbz-Nle-Lys-Arg-Arg)2-[Rh110]
Description:

SMAC/DIABLO [Lys(5-FAM)] is a pro-apoptotic peptide that is derived from the mitochondrial protein known either as Second Mitochondria-Derived Activator of Caspases (Smac) or Direct IAP Binding Protein with low isoelectric point, pI (DIABLO). During apoptosis the mitochondria has increased permeability to Smac/DIABLO, which causes the protein to diffuse into the cytosol. Here, Smac/DIABLO adheres to Inhibitors of apoptosis proteins (IAPs) and prevents them from binding to caspases, which in turn accentuates apoptosis.This peptide has a C-terminal lysine linker labelled with 5-Carboxyfluorescein (5-FAM), a widely used, green fluorescent tag.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,427.7 g/mol
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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