[5-FAM]-PTH (1-34)

Ref. 3D-CRB1100983

Product Information

• Name: [5-FAM]-PTH (1-34)
• Synonyms: 5fam-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-OH[5-FAM]-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-acid[5-FAM]-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-H is-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu- Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH

Description

PTH 1-34, is a biologically active peptide fragment of parathyroid hormone (PTH). PHT 1-34 has been shown to enhance bone fracture healing by promoting osteogenesis. PTH 1-34 also has chondrogenic properties.PTH is an 84-amino-acid polypeptide hormone (PTH 1-84) which is secreted by the parathyroid glands along with its fragments (such as PTH 1-34 and PTH 7-84). PTH increases calcium and decrease phosphate levels in the blood and the abundance of PTH-derived peptides is regulated by blood calcium levels. PTH inhibits the bone growth-promoting activity of osteoblasts and induces osteoclasts to resorb bone and release calcium and phosphate ions into the blood. PTH binds to and activates the receptor parathyroid hormone receptor 1 (PTHR1). PTHR1 is a G-protein-coupled receptor (GPCR) which regulates mineral ion homeostasis, bone turnover and skeletal development.It contains 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag.

• Brand: Biosynth

Chemical properties

• Molecular weight: 4,473.2 g/mol
• Color/Form: Powder