![SMAC/DIABLO-[Cys(AF647)]](https://static.cymitquimica.com/products/3D/img/CRB1110326.png "Click to enlarge")
SMAC/DIABLO-[Cys(AF647)]
Ref. 3D-CRB1110326
| 1mg | 522.00 € | ||
| 100µg | 371.00 € | ||
| 500µg | 452.00 € |
Product Information
- H-AVPIAQKSE(C/AF647)-OH
SMAC/DIABLO-[Cys(AF647)] is a pro-apoptotic peptide that is derived from the mitochondrial protein known either as Second Mitochondria-Derived Activator of Caspases (Smac) or Direct IAP Binding Protein with low isoelectric point, pI (DIABLO). During apoptosis the mitochondria has increased permeability to Smac/DIABLO, which causes the protein to diffuse into the cytosol. Here, Smac/DIABLO adheres to Inhibitors of apoptosis proteins (IAPs) and prevents them from binding to caspases, which in turn accentuates apoptosis.This peptide has a C-terminal cysteine linker labelled with AF647, which is a bright, far-red-fluorescent dye with excitation between 594 nm and 633 nm.
Chemical properties
Technical inquiry about: 3D-CRB1110326 SMAC/DIABLO-[Cys(AF647)]
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