Heat shock protein HSP90 alpha Heavy

Ref. 3D-CRB1300376

Product Information

• Name: Heat shock protein HSP90 alpha Heavy
• Synonyms: H-GVVDSEDLPLNISR^-OH
• Brand: Biosynth
• Description: HSP90 is a family of heat shock proteins (HSPs) which are produced by cells in response to stress signals. HSPs are classified according their molecular mass, where HSP90 represents a family of HSPs with a molecular weight of 90-kDa.The mammalian HSP90 family of proteins is a cluster of highly conserved molecules and their distribution in various cellular compartments underlines their essential roles in cellular homeostasis.HSP90 and its co-chaperones orchestrate crucial physiological processes such as cell survival, cell cycle control, hormone signalling, and apoptosis. Conversely, HSP90, and its secreted forms, contribute to the development and progress of serious pathologies, including cancer and neurodegenerative diseases. Therefore, targeting HSP90 is an attractive strategy for the treatment of neoplasms and other diseases.The arginine residue at position 14 is isotopically labelled with carbon-13 (6) and nitrogen-15 (4).

Chemical properties

• Molecular weight: 1,522.8 g/mol
• Purity: Min. 95%