Apolipoprotein B-100 (APOB100) (1108-1118) Heavy
Ref. 3D-CRB1301564
| 25nMol | 452.00 € |
Product Information
- H-SEIL^AHWSPAK-OH
Apolipoprotein B-100 (apoB-100) is a highly expressed human protein and a novel autoantigen, which is targeted by T- and B-cell immune responses in a subgroup of Lyme arthritis (LA) patients. ApoB-100 is present at high levels in the joint fluid of these patients. The high levels of apoB-100 in joints may lead to antigen presentation of apoB-100 peptides by human leukocyte antigen (HLA)-DR molecules, as well as to T- and B-cell responses to the protein. HLA-DR-presented peptides of apoB-100 have been shown to be immunoreactive. Lyme arthritis (LA) is a late manifestation of infection with the tick-borne spirochete, Borrelia burgdorferi. The leucine residue at position four of this peptide is isotopically labelled with carbon-13 (6) and nitrogen-15 (1), giving this peptide a mass increase of 7 compared to the unlabelled peptide.
Chemical properties
Technical inquiry about: 3D-CRB1301564 Apolipoprotein B-100 (APOB100) (1108-1118) Heavy
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