Anti-MRGPR-X1 antibody - 1mg/mL
Ref. 3D-CRB2005053
| 20µg | 268.00 € | ||
| 100µg | 483.00 € |
Product Information
Primate-specific Mas-related G protein-coupled receptor-X1 (MRGPR-X1) is highly enriched in dorsal root ganglia (DRG) neurones as well as in connective tissue mast cells (CTMC) and the leukaemia-derived human mast cell line (LAD)-2. MRGPR-X1 activation induces acute pain and therefore represents a promising target for future pain therapy.
MRGPR-X1 is activated by bovine adrenal medulla peptide-8-22 (BAM 8-22) which is cleaved from pro-enkephalin by pro-hormone convertases. Unlike most if not all Gq-coupled receptors MRGPR-X1 does not undergo agonist-promoted endocytosis.
Data: Western blot analysis of rat brain preparation.
Lane 1: Rat brain preparation (20µg).
Secondary: Goat anti-rabbit IgG conjugated to HRP 1:5000.
Chemical properties
Technical inquiry about: 3D-CRB2005053 Anti-MRGPR-X1 antibody - 1mg/mL
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