Anti-crc antibody - serum

Ref. 3D-CRB2005253

Product Information

• Name: Anti-crc antibody - serum
• Brand: Biosynth
• Description: Cryptocephal (CRC) is a basic-leucine zipper (bZIP) transcription factor in Drosophila and the homologue of vertebrate activating transcription factor 4 (ATF4), a member of the CREB/ATF family of transcription factors. CRC interacts with EcR-B2 to promote ecdysone-dependent expression of ecdysis triggering hormone (ETH), an essential regulator of insect moulting behaviour. The crc gene is expressed throughout development and mutations in crc causes pleiotropic defects in ecdysone-regulated events during Drosophila moulting and metamorphosis. In third instar larvae, crc expression is high in targets of ecdysone signalling, such as the leg and wing imaginal discs and in the ring gland, where ecdysone is produced.Serum. For use in WB (1:1000) and ELISA (1:1000). Reacts with UniProtKB - Q9VID3_DROME.Image: Anti-crc antibody (crb2005253) (1:1000)Western blot analysis of nuclear extract of Drosophila Schneider 2 cells (S2 cells) (50µg) treated with 2mM DTT to induced by ER stress.Lane 1: S2 cellsLane 2: S2 cells treated with 2mM DTT for 1 hourLane 3: S2 cells treated with 2mM DTT for 6 hoursSecondary: IRDye®800CW Goat anti-Rabbit IgG 1:2000

Chemical properties

• Color/Form: Powder