Anti-crc antibody - serum
Ref. 3D-CRB2005253
| 20µl | 266.00 € | ||
| 100µl | 479.00 € |
Product Information
Cryptocephal (CRC) is a basic-leucine zipper (bZIP) transcription factor in Drosophila and the homologue of vertebrate activating transcription factor 4 (ATF4), a member of the CREB/ATF family of transcription factors. CRC interacts with EcR-B2 to promote ecdysone-dependent expression of ecdysis triggering hormone (ETH), an essential regulator of insect moulting behaviour. The crc gene is expressed throughout development and mutations in crc causes pleiotropic defects in ecdysone-regulated events during Drosophila moulting and metamorphosis. In third instar larvae, crc expression is high in targets of ecdysone signalling, such as the leg and wing imaginal discs and in the ring gland, where ecdysone is produced.
Serum. For use in WB (1:1000) and ELISA (1:1000). Reacts with UniProtKB - Q9VID3_DROME.
Image: Anti-crc antibody (crb2005253) (1:1000)
Western blot analysis of nuclear extract of Drosophila Schneider 2 cells (S2 cells) (50µg) treated with 2mM DTT to induced by ER stress.
Lane 1: S2 cells
Lane 2: S2 cells treated with 2mM DTT for 1 hour
Lane 3: S2 cells treated with 2mM DTT for 6 hours
Secondary: IRDye®800CW Goat anti-Rabbit IgG 1:2000
Chemical properties
Technical inquiry about: 3D-CRB2005253 Anti-crc antibody - serum
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