Anti-TAS2R39 antibody - 2mg/mL

Ref. 3D-CRB2005729

Product Information

• Name: Anti-TAS2R39 antibody - 2mg/mL
• Brand: Biosynth
• Description: Bitter taste receptors (TAS2Rs) are predominantly found in the mouth and other tissues, including the gut and lungs, and cell types such as immune cells. Â Taste receptor type 2 member 39 (TAS2R39) is a receptor that plays a prominent role in the perception of bitterness. TAS2R39 may also play a role in sensing the chemical composition of the gastrointestinal content. The activity of the TAS2R39 receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. TAS2Rs recognise a wide variety of compounds, and work with TAS2R39 has helped identify antagonist compounds to block the perceived bitterness of medications. 6-methoxyflavanones are antagonists of TAS2R39, the methoxy group on the 6-position of the flavanone's A-ring is the critical region for exerting inhibitory activity.