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[4-(Propan-2-yloxy)-2-(trifluoromethyl)phenyl]methanamine
CAS: 1152574-77-0
Ref. 3D-CWB57477
| 1g | 863.00 € | ||
| 100mg | 219.00 € |
Product Information
4-(Propan-2-yloxy)-2-(trifluoromethyl)phenyl]methanamine is a potent and selective small molecule antagonist of the α7 nicotinic acetylcholine receptor. It inhibits the binding of nicotine to the α7 nicotinic acetylcholine receptor with an IC50 value of 0.06 μM, and it shows no activity at other nicotinic receptors. 4-(Propan-2-yloxy)-2-(trifluoromethyl)phenyl]methanamine has been used as a pharmacological tool to study ion channels, such as calcium channels, potassium channels, and sodium channels. This compound has also been shown to inhibit protein interactions with the α7 nicotinic acetylcholine receptor by binding to the ligand binding site on the receptor.
Chemical properties
Technical inquiry about: 3D-CWB57477 [4-(Propan-2-yloxy)-2-(trifluoromethyl)phenyl]methanamine
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