5S,12R,18R-Trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid
CAS: 552830-51-0
Ref. 3D-CXA83051
| 1mg | To inquire |
Product Information
5S,12R,18R-Trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid (5S,12R-HPETE) is a potent activator of the TRPA1 ion channel. It binds to the receptor in a cooperative manner with other molecules and activates it. 5S,12R-HPETE also inhibits the activity of protein kinase C and phospholipase A2. It has been used as a research tool to study the molecular mechanisms of inflammation and pain sensation. 5S,12R-HPETE is also a ligand for the prostaglandin receptor EP4 and has been shown to have anti-inflammatory effects in vitro.
Chemical properties
Technical inquiry about: 3D-CXA83051 5S,12R,18R-Trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid
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