Product Information
- 1,3-Benzenedicarboxamide, 5-Amino-
- 5-Aminoisophthalamide
5-Amino-isophthalamide (5AIP) is a molecule that can be used as a molecular probe for the reticulum. It has been shown to inhibit protein synthesis in vivo and in vitro. 5AIP binds to the 30S ribosomal subunit, preventing the binding of aminoacyl-tRNA and peptidyl-tRNA to the acceptor site on the ribosome. This prevents the formation of a peptide bond between two amino acids, which is required for protein synthesis. The binding of 5AIP to the 30S ribosomal subunit also inhibits translation by preventing peptidyltransferase from transferring tRNA from its A site to P site. In addition, 5AIP binds to lanthanide ions such as terbium and europium, which can be used in diagnostic techniques such as fluorescence spectroscopy or magnetic resonance imaging. 5AIP is also an amide with one chiral carbon
Chemical properties
Technical inquiry about: 3D-DBA32149 5-Amino-isophthalamide
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