3-Hydroxy guanfacine
CAS: 78197-84-9
Ref. 3D-DDA19784
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
Guanfacine is a drug that is used to treat high blood pressure, anxiety disorders, and attention-deficit hyperactivity disorder. It is an alpha2A receptor agonist and thus it has antihypertensive, antidepressant, and antipsychotic effects. Guanfacine can be metabolized through a number of metabolic transformations, including sulfation and glucuronidation. The methylation of guanfacine by catechol-O-methyltransferase (COMT) produces the active form of the drug, 3-hydroxy guanfacine. This active form can then be metabolized through monooxidation or enzymatic hydrolysis to produce metabolites that are more polar than the parent compound. Guanfacine is also an antagonist at postsynaptic alpha2B receptors and it has been shown to inhibit catecholamine synthesis in animals.
Guanfacine's chromatographic properties have been studied extensively and it has been shown to elute with other drugs
Chemical properties
Technical inquiry about: 3D-DDA19784 3-Hydroxy guanfacine
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
