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3-Hydroxy guanfacine
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3-Hydroxy guanfacine

CAS: 78197-84-9

Ref. 3D-DDA19784

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Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
3-Hydroxy guanfacine
Synonyms:
  • N-(Aminoiminomethyl)-2,6-dichloro-3-hydroxybenzeneacetamide
  • Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-3-hydroxy-
Description:

Guanfacine is a drug that is used to treat high blood pressure, anxiety disorders, and attention-deficit hyperactivity disorder. It is an alpha2A receptor agonist and thus it has antihypertensive, antidepressant, and antipsychotic effects. Guanfacine can be metabolized through a number of metabolic transformations, including sulfation and glucuronidation. The methylation of guanfacine by catechol-O-methyltransferase (COMT) produces the active form of the drug, 3-hydroxy guanfacine. This active form can then be metabolized through monooxidation or enzymatic hydrolysis to produce metabolites that are more polar than the parent compound. Guanfacine is also an antagonist at postsynaptic alpha2B receptors and it has been shown to inhibit catecholamine synthesis in animals.
Guanfacine's chromatographic properties have been studied extensively and it has been shown to elute with other drugs

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
262.09 g/mol
Formula:
C9H9Cl2N3O2
Purity:
Min. 95%
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Hazard Info

UN Number:
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Forbidden to fly:
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