Miboplatin
CAS:
Ref. 3D-DEA77575
Product Information
Miboplatin is a chemotherapeutic agent that is used to treat cancer and other diseases. It inhibits DNA synthesis by binding to the enzyme topoisomerase II, which maintains the integrity of DNA. Miboplatin has been shown to be cytotoxic at doses of 0.5-2 micrograms/mL in vitro against k562 cells in human serum. It has also been shown to have carcinogenic potential in rats, although not in mice. Miboplatin is given as an oral preparation with sodium carbonate, which reacts with miboplatin to form a solution containing miboplatin and sodium bicarbonate (NaHCO). This solution can be analyzed by various analytical methods, such as thin-layer chromatography (TLC) or gas chromatography (GC). Control analysis is also performed on this solution before administration to the patient. Miboplatin has been studied as a treatment for inflammatory bowel disease and has been found to be
Chemical properties
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