Product Information
Name:1-Phenyl-3-pyrrolidinone
Brand:Biosynth
Description:1-Phenyl-3-pyrrolidinone (1PP) is a cytotoxic agent that inhibits the growth of tumor cells. It has been shown to have activity against leukemia, lymphocytic leukemia, and human colon adenocarcinoma cells. The 1PP binds to the phenyl ring and interacts with DNA in a manner similar to adriamycin. This binding blocks DNA synthesis, leading to cell death by apoptosis. 1PP is resistant to leucovorin, which is an antagonist of adriamycin and other chemotherapeutic agents. In vitro studies have shown that 1PP exhibits cytotoxicity against promyelocytic leukemia Hl-60 cells and Molt-4 cells.
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Chemical properties
Molecular weight:161.2 g/mol
Formula:C10H11NO
Purity:Min. 95%
Technical inquiry about: 1-Phenyl-3-pyrrolidinone
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