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1-Phenyl-3-pyrrolidinone

CAS:

Ref. 3D-DFA12002

5g
978.00€
500mg
348.00€
1-Phenyl-3-pyrrolidinone
Biosynth

Product Information

Name:1-Phenyl-3-pyrrolidinone
Brand:Biosynth
Description:1-Phenyl-3-pyrrolidinone (1PP) is a cytotoxic agent that inhibits the growth of tumor cells. It has been shown to have activity against leukemia, lymphocytic leukemia, and human colon adenocarcinoma cells. The 1PP binds to the phenyl ring and interacts with DNA in a manner similar to adriamycin. This binding blocks DNA synthesis, leading to cell death by apoptosis. 1PP is resistant to leucovorin, which is an antagonist of adriamycin and other chemotherapeutic agents. In vitro studies have shown that 1PP exhibits cytotoxicity against promyelocytic leukemia Hl-60 cells and Molt-4 cells.
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Chemical properties

Molecular weight:161.2 g/mol
Formula:C10H11NO
Purity:Min. 95%

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