Product Information
- Asimadoline [INN]
- Benzeneacetamide, N-((1S)-2-((3S)-3-hydroxy-1-pyrrolidinyl)-1-phenylethyl)-N-methyl-alpha-phenyl-
- Benzeneacetamide, N-(2-(3-hydroxy-1-pyrrolidinyl)-1-phenylethyl)-N-methyl-alpha-phenyl-, (S-(R*,R*))-
- Benzeneacetamide, N-[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]-N-methyl-α-phenyl-
- Benzeneacetamide, N-[2-(3-hydroxy-1-pyrrolidinyl)-1-phenylethyl]-N-methyl-α-phenyl-, [S-(R*,R*)]-
- Emd 61753
- N-((alpha S)-alpha-((3S)-3-Hydroxy-1-pyrrolidinyl)methyl)benzyl)-N-methyl-2,2-diphenylacetamide
- N-((alphaS)-alpha-(((3S)-3-Hydroxy-1-pyrrolidinyl)methyl)benzyl)-N-methyl-2,2-diphenylacetamide
- N-[(1S)-2-[(3S)-3-Hydroxy-1-pyrrolidinyl]-1-phenylethyl]-N-methyl-α-phenylbenzeneacetamide
- N-{(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl}-N-methyl-2,2-diphenylacetamide
- See more synonyms
- Unii-D0Vk52Nv5M
Asimadoline is a compound that has been shown to have analgesic and anti-inflammatory effects. It binds to κ-opioid receptors, which are found in the central nervous system and gastrointestinal tract. Asimadoline also binds to kappa-opioid receptors, which are located on immune cells in the brain and spinal cord. This drug has been shown to inhibit the production of pro-inflammatory cytokines, such as TNF-α and IL-1β, which may be due to activation of κ-opioid receptors. Asimadoline has also been shown to inhibit Pgp substrate activity, which may explain its ability to treat bowel disease, primary sclerosing cholangitis (PSC), inflammatory bowel disease (IBD), diabetic neuropathy, and antinociceptive disorders.
Chemical properties
Technical inquiry about: 3D-DGA20546 Asimadoline
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
