MonoMe Auristatin D
CAS: 203849-91-6
Ref. 3D-DIA84991
| 5mg | 101.00 € | ||
| 10mg | 162.00 € | ||
| 25mg | 270.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 588.00 € |
Product Information
- MMAD
MonoMe Auristatin D is a water-soluble, non-toxic, and highly potent analogue of dolastatin 10. It has been shown to be effective against Gram-positive bacteria including methicillin resistant Staphylococcus aureus (MRSA). The antimicrobial activity of MonoMe Auristatin D is mediated by its binding to the ribosomes in the bacterial cell membrane. This binding prevents the production of proteins vital for cell division. MonoMe Auristatin D has also been shown to inhibit DNA synthesis in vitro and in vivo.
The FTIR spectroscopy data show that MonoMe auristatin D can form hydrogen bonds with the amide group of amino acids such as proline and lysine.
Chemical properties
Technical inquiry about: 3D-DIA84991 MonoMe Auristatin D
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