pep2-SVKI
CAS: 328944-75-8
Ref. 3D-DNA94475
1mg | 338.00 € | ||
5mg | 534.00 € | ||
10mg | 814.00 € | ||
25mg | 1,437.00 € | ||
50mg | 2,298.00 € |
Product Information
- Pep2-Svki
Pep2 is a potent, selective, and orally active positive allosteric modulator of the AMPA receptor. It binds to the GluR2 subunit at the synapse and increases the probability of glutamate release. Pep2-SVKI is a modified form of the peptide that has been shown to have potentiating effects on retinal ganglion cells in vitro. Pep2-SVKI is also able to induce depression in postsynaptic neurons by increasing potassium channel activity and reducing neurotransmitter release. The precise mechanism by which pep2-SVKI induces depression is not yet known, but it may be due to its ability to interact with cytosolic proteins or its potential interaction with cellular signaling pathways in neurons.
Chemical properties
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