NHS-Biotin

CAS: 35013-72-0

Ref. 3D-DPG-5707

Product Information

• Name: NHS-Biotin
• Brand: Biosynth
• Description: NHS-Biotin is a biotin analog that can be used as an affinity label for the purification of specific proteins. NHS-Biotin is synthesized by reacting monoclonal antibody with lysine residues and a hydroxyl group, which form a covalent bond known as an amide linkage. The NHS-Biotin can then be covalently attached to the protein of interest. This attachment allows the protein to be purified by passing it over a column of immobilized streptavidin. NHS-Biotin has been shown to bind to actin filaments in humans and uptake peptide hormones in the bloodstream. It was also found that human serum contains chemical reactions with NHS-Biotin, forming a disulfide bond between two cysteine residues on the protein.

Chemical properties

• Molecular weight: 660.64 g/mol
• Formula: C₂₈H₃₉F₃N₆O₉
• Purity: Min. 95%