Product Information
Name:PF-04418948
Brand:Biosynth
Description:PF-04418948 is a potent and selective antagonist of the camp receptor. It inhibits the binding of camp to the receptor, thereby inhibiting activation of downstream signaling pathways. PF-04418948 has been shown to inhibit cyclase activity in vitro, which may account for its effects on PGE2 levels. PF-04418948 also prevents cytosolic Ca2+ accumulation by blocking cation channels, which may contribute to its neuroprotective effects. PF-04418948 has been shown to have anti-angiogenic properties in vivo and in vitro experiments. This drug also blocks glutamate release from activated microglia and toll-like receptor signaling pathways, thereby suppressing microbial infection.
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Chemical properties
Molecular weight:409.41 g/mol
Formula:C23H20FNO5
Purity:Min. 95%
Technical inquiry about: PF-04418948
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