PF-04418948
CAS: 1078166-57-0
Ref. 3D-DTB16657
| 5mg | 348.00 € | ||
| 10mg | 406.00 € | ||
| 25mg | 677.00 € | ||
| 50mg | 1,033.00 € | ||
| 100mg | 1,556.00 € |
Product Information
- Pf 04418948
- 1-(4-Fluorobenzoyl)-3-[(6-Methoxynaphthalen-2-Yl)Oxymethyl]Azetidine-3-Carboxylic Acid
PF-04418948 is a potent and selective antagonist of the camp receptor. It inhibits the binding of camp to the receptor, thereby inhibiting activation of downstream signaling pathways. PF-04418948 has been shown to inhibit cyclase activity in vitro, which may account for its effects on PGE2 levels. PF-04418948 also prevents cytosolic Ca2+ accumulation by blocking cation channels, which may contribute to its neuroprotective effects. PF-04418948 has been shown to have anti-angiogenic properties in vivo and in vitro experiments. This drug also blocks glutamate release from activated microglia and toll-like receptor signaling pathways, thereby suppressing microbial infection.
Chemical properties
Technical inquiry about: 3D-DTB16657 PF-04418948
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