Cevidoplenib
CAS: 1703788-21-9
Ref. 3D-DTC78821
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire |
Product Information
Cevidoplenib is a small molecule inhibitor of the receptor tyrosine kinase RET, which is associated with a variety of cancers. It binds to the active site of RET, preventing activation and causing RET to be degraded. Cevidoplenib inhibits the phosphorylation of tyrosine residues on RET, thereby blocking RET-mediated signaling cascades. This inhibition leads to decreased cell proliferation and survival in vitro and in vivo. Cevidoplenib is currently in phase II clinical trials for patients with thyroid cancer or medullary thyroid carcinoma.
Chemical properties
Technical inquiry about: 3D-DTC78821 Cevidoplenib
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