tert-Butyl 3-(3-bromophenyl)azetidine-1-carboxylate

CAS: 1203681-54-2

Ref. 3D-DYB68154

Product Information

• Name: tert-Butyl 3-(3-bromophenyl)azetidine-1-carboxylate
• Brand: Biosynth
• Description: Tert-butyl 3-(3-bromophenyl)azetidine-1-carboxylate (TBAc) is an inhibitor of 3-hydroxyacyl coenzyme A dehydrogenase. It is used as a probe in the study of the structural biology and mechanism of action of this enzyme, which is involved in fatty acid and cholesterol biosynthesis. TBAc has been shown to inhibit the cationic polymerization process, which may indicate its potential use as a cancer therapeutic. The reaction mechanism involves hydrogen bonding and activation energies that are influenced by dihedral angles and p-450 enzymes. TBAc has also been shown to have a strong affinity for trifluoroacetic acid (TFA), which may be due to the formation of an ionic bond between TBAc and TFA.

Chemical properties

• Molecular weight: 312.2 g/mol
• Formula: C₁₄H₁₈BrNO₂
• Purity: Min. 95%