Product Information
Name:Nitracrine
Brand:Biosynth
Description:Nitracrine is a nitro-nitrosourea derivative that inhibits DNA synthesis in cells by binding to the dna template as a mononucleotide. It has been shown to have potent cytotoxic effects on solid tumour cells and is considered a promising anticancer agent. Nitracrine also inhibits cell division by inhibiting RNA synthesis, DNA synthesis, and protein synthesis. It has been found to be more effective than other nitrosoureas such as 5-fluorouracil or methotrexate at inhibiting RNA synthesis. Nitracrine has also been shown to induce apoptosis in certain cancerous cells. The optimum concentration of nitracrine appears to be between 10 µM and 100 µM when used with K562 cells.
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Chemical properties
Molecular weight:324.4 g/mol
Formula:C18H20N4O2
Purity:Min. 95%
Technical inquiry about: Nitracrine
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