2-prop-2-ynoxyisoindoline-1,3-dione

CAS: 4616-63-1

Ref. 3D-EAA61663

Product Information

• Name: 2-prop-2-ynoxyisoindoline-1,3-dione
• Synonyms: 1H-Isoindole-1,3(2H)-dione, 2-(2-propyn-1-yloxy)-, 1H-Isoindole-1,3(2H)-dione, 2-(2-propynyloxy)-, 2-(2-Propyn-1-yloxy)-1H-isoindole-1,3(2H)-dione, 2-(Prop-2-yn-1-yloxy)-2,3-dihydro-1H-isoindole-1,3-dione, 2-(Prop-2-yn-1-yloxy)isoindoline-1,3-dione, 2-(Prop-2-ynyloxy)-isoindole-1,3-dione, 2-(prop-2-yn-1-yloxy)-1H-isoindole-1,3(2H)-dione, 2-Prop-2-ynoxyisoindole-1,3-dione, N-(prop-2-ynyloxy)phthalimide, N-Propargyloxyphthalimide, NSC 80674, Phthalimide, N-(2-propynyloxy)-
• CAS: 4616-63-1

Description

2-Prop-2-ynoxyisoindoline-1,3-dione is a multifunctional pyridine derivative with potential anticancer activity. It has been shown to inhibit HDAC and panobinostat, an inhibitor of histone deacetylase. 2-Prop-2-ynoxyisoindoline-1,3-dione has a solubility of less than 20 mg/mL in most solvents and is insoluble in water. This compound has been shown to have a low yield when synthesized from 2,6-dichloropyridine. These properties are advantageous for cell culture studies because they allow for the detection of changes in cellular morphology and the frequency of cell division. 2-Prop-2-ynoxyisoindoline-1,3-dione also has an activated aromatic ring that can be used as a prodrug to activate other compounds that need activation at this site (e.g., transition metals).

• Brand: Biosynth

Chemical properties

• Molecular weight: 201.18 g/mol
• Formula: C₁₁H₇NO₃
• Purity: Min. 95%