α-Lapachone
CAS: 4707-33-9
Ref. 3D-EAA70733
1mg | To inquire | ||
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire |
Product Information
- 2,2-Dimethyl-3,4-dihydrobenzo[g]chromene-5,10-dione
- 2H-naphtho[2,3-b]pyran-5,10-dione, 3,4-dihydro-2,2-dimethyl-
- 3,4-Dihydro-2,2-dimethyl-2H-naphtho[2,3-b]pyran-5,10-dione
- NSC 26327
- NSC 629747
α-Lapachone is a synthetic analog of lapachol. It binds to topoisomerase, which prevents the enzyme from cutting and separating the two strands of DNA. This inhibition causes DNA damage that leads to cell death by necrosis or apoptosis. α-Lapachone also has anticancer activity against murine leukemia cells in culture. α-Lapachone exhibits low cytotoxicity and does not affect healthy cells in culture.
Chemical properties
Technical inquiry about: 3D-EAA70733 α-Lapachone
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