Product Information
- 2,4(3H,5H)-Furandione
- 4-Hydroxy-2(5H)-furanone
- Acetoacetic acid, 4-hydroxy-, γ-lactone
- Beta-Oxo-Gamma-Butyrolactone
- Butanoic acid, 4-hydroxy-3-oxo-, γ-lactone
- Dihydro-2,4-furandione
- Oxolane-2,4-dione
- Tetrahydro-2,4-furandione
- Tetrahydrofuran-3,5-dione
- Tetronic acid
- See more synonyms
- Tetronicacidmin
- furan-2,4(3H,5H)-dione
Furan-2,4-dione is a hydroxylated furan derivative that is used as an antimicrobial agent. It has a high degree of resistance to hydrochloric acid and human serum. Furan-2,4-dione reacts with the thiol groups on the mitochondrial membrane potential to create a disulfide bond, which leads to depolarization of the mitochondria and cell death. Furan-2,4-dione also inhibits tetronic acid dehydrogenase and tetronic acid reductase enzymes in cancer cells, leading to inhibition of tumor growth. The structure of furan-2,4-dione consists of a bicyclic heterocycle with basic properties.
Chemical properties
Technical inquiry about: 3D-EAA97156 Furan-2,4-dione
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