6-Bromo-2-naphthyl b-D-glucuronide

CAS: 22720-35-0

Ref. 3D-EB03245

Product Information

• Name: 6-Bromo-2-naphthyl b-D-glucuronide
• Synonyms: Br-Nap-a-D-GlcA2-(6-Bromonaphthyl) b-D-glucuronide
• Brand: Biosynth
• Description: 6-Bromo-2-naphthyl beta-D-glucuronide is a substrate for beta-glucuronidase, an enzyme involved in detoxification and bacterial metabolism. Upon enzymatic hydrolysis, it releases 6-bromo-2-naphthol, which forms a detectable dye when reacted with diazonium salts. This compound is widely used in microbiology to detecting E. coli in water testing and histochemical staining. 6-Bromo-2-naphthyl beta-D-glucuronide is also been used in cancer research studies. It has been found that some tumors are related to a high activity of beta-glucuronidase, responsible to reactivate the carcinogens and promote tumor progression, developing a drug resistance to chemotherapy.

Chemical properties

• Molecular weight: 399.2 g/mol
• Formula: C₁₆H₁₅BrO₇
• Purity: Min 97%
• Color/Form: White Off-White Powder