Product Information
Azepane-2,4-dione is a reactive intermediate in the synthesis of quinolines. It can be synthesized by acid treatment of benzofuran, followed by condensation with piperidine and quinone, or by condensation of 2-aminoethanethiol with chloroacetyl chloride. Azepane-2,4-dione is not stable and spontaneously reacts with water to form an adduct. The compound can be converted to the corresponding quinoline through a two step process involving enamine formation and cyclization. This reaction is catalyzed by palladium on carbon or stannic chloride on alumina.
Chemical properties
Technical inquiry about: 3D-EBA52088 Azepane-2,4-dione
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