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Product Information
1,8-Naphthyridin-4-amine is a genotoxic compound that has been detected in human glioblastoma cells. It can be used to investigate the molecular mechanism of cancer and the carcinogenesis process. 1,8-Naphthyridin-4-amine binds to DNA polymerase and inhibits its activity, which prevents the replication of DNA. This drug also induces p53 activation and increases chloride levels in cancer cells. 1,8-Naphthyridin-4-amine has also been shown to cause DNA repair by base excision.
Chemical properties
Technical inquiry about: 3D-ECA56930 1,8-Naphthyridin-4-amine
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