Product Information
MMP-3 is a protein that is active in the human body and plays an important role in the breakdown of extracellular matrix. It has been shown to be involved in the disease activity of multiple sclerosis and rheumatoid arthritis. MMP-3 is synthesized as a proenzyme, which contains a signal peptide that directs it to the endoplasmic reticulum (ER). The proenzyme can be activated by two mechanisms: autocatalytic cleavage or by proteolytic cleavage by other enzymes such as serine proteases or metalloproteinases. Calcium pantothenate inhibits MMP-3 activation by autocatalytic cleavage, while nonsteroidal anti-inflammatory drugs inhibit proteolytic cleavage. Transfection experiments have shown that MMP-3 interacts with toll-like receptor 2 (TLR2) and TLR4, which are proteins found on cell surfaces that bind to pathogen
Chemical properties
Technical inquiry about: 3D-EDA95599 MMP-3
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
