Product Information
- (2,4-Dinitrophenyl)ethylenediamine
- 1,2-Ethanediamine, N-(2,4-dinitrophenyl)-
- 1,2-Ethanediamine, N<sup>1</sup>-(2,4-dinitrophenyl)-
- 1,2-Ethanediamine, N~1~-(2,4-dinitrophenyl)-
- Ethylenediamine, N-(2,4-dinitrophenyl)-
- N-(2,4-Dinitrophenyl)ethylenediamine
- N-(2-Aminoethyl)-2,4-dinitroaniline
- N<sup>1</sup>-(2,4-Dinitrophenyl)-1,2-ethanediamine
EDDnp is a potent and selective inhibitor of the proteolytic enzyme dipeptidyl peptidase IV (DPP-IV). EDDnp binds to the active site of DPP-IV, which prevents it from cleaving peptides at the carboxy terminus. The inhibition of DPP-IV results in an increase of peptide hormones such as glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP), which are involved in regulating blood glucose levels. In addition, there are high values of EDDnp in human serum and urine, which may be due to its function as a potential biomarker for diabetes. The physiological function of EDDnp is still being investigated.
Chemical properties
Technical inquiry about: 3D-EDP-5012-PI EDDnp
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