Product Information
- 6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione
- 6-(1H-imidazol-1-yl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione hydrochloride
- 6-(1H-imidazol-1-yl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione
YM 90K hydrochloride is a voltage-gated calcium channel antagonist that blocks the influx of calcium ions into cells. It is a competitive inhibitor of the neurotransmitter glutamate and prevents neuronal death by inhibiting the release of glutamate. YM 90K hydrochloride has been shown to be clinically relevant in humans, as it binds to receptors on the surface of neurons and prevents voltage-dependent calcium channels from opening. This binding leads to an increase in the frequency of action potentials in the brain, which may lead to brain infarction. YM 90K hydrochloride also inhibits organic anion transporters (OAT) at higher doses, which leads to increased concentrations of estrone sulfate, a metabolite associated with hormone replacement therapy.
Chemical properties
Technical inquiry about: 3D-EGA16430 YM 90K hydrochloride
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