Product Information
MRX-2843 is a small molecule that inhibits the tyrosine kinase activity of Flt3. Flt3 is a receptor tyrosine kinase which plays an important role in T-cell leukemia, autoimmune diseases, and inflammation. MRX-2843 also has anti-infective properties and can be used to treat bacterial infections such as tuberculosis. In preclinical studies MRX-2843 was shown to inhibit the growth of cancer cells in cell culture and xenograft models. It also showed efficacy against wild-type mice with leukemia when administered orally or intravenously, but not when given topically.
Chemical properties
Technical inquiry about: 3D-EHC88207 MRX-2843
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