4-Methylumbelliferyl a-D-mannopyranoside

CAS: 28541-83-5

Ref. 3D-EM03179

Product Information

• Name: 4-Methylumbelliferyl a-D-mannopyranoside
• Synonyms: 4-MU-a-D-Man
• Brand: Biosynth
• Description: 4-Methylumbelliferyl alpha-D-mannopyranoside (4-MU-a-D-Man) is a fluorogenic substrate used in activity assays for alpha-mannosidase. When it is hydrolyzed by alpha-mannosidase, it produces a fluorescent compound, 4-methylumbelliferone (4-MU). 4-MU-a-D-Man is often used in medical research to monitor the activity of alpha-mannosidase, which is important in lysosomal storage diseases. In addition, 4-Methylumbelliferyl alpha-D-mannopyranoside has been used to study the the activity of concanavalin A, a lectin that specifically binds to alpha-D-mannopyranosyl and alpha-D-glucopyranosyl residues on various glycoproteins. The use of this fluorogenic enzyme substrate permits study the degree of alpha-D-mannosidic linkage cleavage by the enzyme.

Chemical properties

• Molecular weight: 338.31 g/mol
• Formula: C₁₆H₁₈O₈
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder