4-Methylumbelliferyl a-L-idopyranoside

CAS: 66901-41-5

Ref. 3D-EM03200

Product Information

• Name: 4-Methylumbelliferyl a-L-idopyranoside
• Brand: Biosynth
• Description: 4-Methylumbelliferyl alpha-L-idopyranoside is a fluorogenic substrate for alpha-L-iduronidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl alpha-L-idopyranosideas a substrate for measuring the alpha-L-iduronidase activity is used for Mucopolysaccharidosis I diagnosis and Hurler syndrome screening.

Chemical properties

• Molecular weight: 338.31 g/mol
• Formula: C₁₆H₁₈O₈
• Purity: Min. 98 Area-%
• Color/Form: White Powder