4-Methylumbelliferyl-α-L-rhamnopyranoside

CAS: 106488-05-5

Ref. 3D-EM05131

Product Information

• Name: 4-Methylumbelliferyl-α-L-rhamnopyranoside
• Synonyms: 4-MU-a-L-Rha
• Brand: Biosynth
• Description: 4-Methylumbelliferyl-alpha-L-rhamnopyranoside is a fluorogenic substrate for alpha-L-rhamnosidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl-alpha-L-rhamnopyranosideas a substrate for measuring the alpha-L-rhamnosidase activity is used for detection of bacterial infection.

Chemical properties

• Molecular weight: 322.32 g/mol
• Formula: C₁₆H₁₈O₇
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C16H18O7/c1-7-5-12(17)23-11-6-9(3-4-10(7)11)22-16-15(20)14(19)13(18)8(2)21-16/h3-6,8,13-16,18-20H,1-2H3/t8-,13-,14+,15+,16-/m0/s1
• InChI key: InChIKey=CQKHENXHLAUMBH-JKNOJPNLSA-N
• SMILES: Cc1cc(=O)oc2cc(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)ccc12